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Type Debuff
Effects -10 defense
-10% damage reduction
+5% damage
+50% minion knockback
+5% movement speed (if player)
-10 health per second (if enemy)
Tooltip Your skin is burning off

Irradiated is a debuff with different effects depending on what it has inflicted. If inflicted on the player, they receive various stat increases and decreases. The Lead Core accessory, dropped by Irradiated Slimes and Gamma Slimes, provides immunity to this debuff. If inflicted on an enemy, their health decreases over time. All enemies immune to either Poisoned or Crush Depth are also immune to Irradiated.

Causes[edit | edit source]

From player[edit | edit source]

From Duration Chance
Ethereal Extorter Ethereal Extorter 5 seconds (On rogue hits) 100% in the Sulphurous Sea biome
Helium Flash Helium Flash 15 seconds (Projectile) 100%
Karasawa Karasawa 5 seconds 100%
Basher Basher 2 seconds 100%
Contaminated Bile Contaminated Bile 4 seconds 100%
Nuclear Rod Nuclear Rod 2 seconds (Irradiated Aura) 100%
Star-Tainted Generator Star-Tainted Generator 3 seconds (On minion hits) 100%
Miasma Miasma 3 seconds 100%
Acidic Rain Barrel Acidic Rain Barrel 3 seconds (Shrapnel)
3-5 seconds (Droplet)
Corrosive Spine Corrosive Spine 2 seconds (Clouds) 100%
Flak Toxicannon Flak Toxicannon 5 seconds (Blast)
3 seconds (Droplet)
Belching Saxophone Belching Saxophone 3 seconds (Reed)
5 seconds (Bubble)
Slithering Eels Slithering Eels 3 seconds (Eel)
1 second (Droplet)
Skyfin Bombers Skyfin Bombers 2 seconds (Nuke, Cloud)
3 seconds (Irradiated Aura)
Spent Fuel Container Spent Fuel Container 10 seconds
20 seconds (Stealth Strike)
Sulphurous Grabber Sulphurous Grabber 2 seconds (Yoyo) 100%
Rusty Beacon Prototype Rusty Beacon Prototype 1 seconds (Rust shards) 100%
Rusty Medallion Rusty Medallion 3 seconds (Droplet) 100%
Corroded Caustibow Corroded Caustibow 2 seconds (Aura)
1 second (Shell)
Parasitic Scepter Parasitic Scepter 4 seconds (Leeches) 100%
Star Swallower Containment Unit Star Swallower Containment Unit 3 seconds (Droplets) 100%

From Calamity NPCs[edit | edit source]

From Duration Chance
Irradiated Slime Irradiated Slime 5 seconds 100%
Radiator Radiator Infinite 100%
Skyfin Skyfin 3 seconds 100%
Nuclear Terror Nuclear Terror 5 seconds (contact) 100%
Tooth Ball Tooth Ball (Old Duke) 3 seconds (Contact) 100%
Cragmaw Mire Cragmaw Mire 5 seconds 100%
Gamma Slime Gamma Slime 3 seconds 100%
Nuclear Toad Nuclear Toad 5 seconds (Contact)
3 seconds (Goo)
Acid Eel Acid Eel 3 seconds (Contact) 100%
Trilobite Trilobite 4 seconds (Contact) 100%
Water Leech Water Leech 2 seconds (Contact) 100%
Flak Crab Flak Crab 2 seconds (Flak Shot) 100%
Sulphurous Skater Sulphurous Skater 2 seconds (Contact) 100%

Notes[edit | edit source]

  • While the player has the Old Duke's Lore item in their inventory, the Irradiated debuff increases their defense and damage reduction instead of decreasing it.

Trivia[edit | edit source]

  • Irradiated's name was reverted after being previously known as Acid Rain, which was a debuff inflicted on the player during the Acid Rain event.